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Terlipressin dose calculator

Reported study range for hepatorenal syndrome (HRS-AKI): 0.851.7 mg every 6 hours for up to 14 days (intravenous). Convert it below, including draw volume and syringe units.

Convert your Terlipressin dose
Vial
Result
Converted amount0.85 mg
Dose mass850 mcg
Concentration2,500 mcg/mL
Draw volume0.34 mL
U-100 syringe34 units
Reported study ranges
PurposeRouteReported rangeFrequency
hepatorenal syndrome (HRS-AKI)intravenous0.851.7 mgevery 6 hours for up to 14 days

Ranges are reported from the literature for research context only. They are not a protocol and not a recommendation.

Concentration by vial and diluent
Vial1 mL diluent2 mL diluent3 mL diluent
2 mg2,000 mcg/mL1,000 mcg/mL667 mcg/mL
5 mg5,000 mcg/mL2,500 mcg/mL1,667 mcg/mL
10 mg10,000 mcg/mL5,000 mcg/mL3,333 mcg/mL

Concentration is vial mass divided by diluent volume. Reconstitution volume changes what you draw, never the dose itself.

What to draw for 850 mcg
VialDiluentDraw volumeU-100 unitsDoses per vial
2 mg1 mL0.425 mL42.5 units2
2 mg2 mL0.85 mL85 units2
2 mg3 mL1.275 mL127.5 units2
5 mg1 mL0.17 mL17 units6
5 mg2 mL0.34 mL34 units6
5 mg3 mL0.51 mL51 units6
10 mg1 mL0.085 mL8.5 units12
10 mg2 mL0.17 mL17 units12
10 mg3 mL0.255 mL25.5 units12

Calculated for the low end of the reported hepatorenal syndrome (HRS-AKI) range. Change the dose in the calculator above for any other amount.

Terlipressin at a glance
~50 minutes (terlipressin); ~3 hours (active metabolite lysine-vasopressin)
Half-life
1,227.37 Da
Molecular weight
intravenous
Routes
prescription
Legal status
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