Pasireotide dose calculator

Reported study range for Cushing's disease: 300–900 mcg twice daily (subcutaneous). Convert it below, including draw volume and syringe units.

Convert your Pasireotide dose

Amount

From

To

Vial

Vial amount (mg)

Diluent volume (mL)

Result

Converted amount0.3 mg

Dose mass300 mcg

Concentration2,500 mcg/mL

Draw volume0.12 mL

U-100 syringe12 units

Reported study ranges

Purpose	Route	Reported range	Frequency
Cushing's disease	subcutaneous	300–900 mcg	twice daily
acromegaly (LAR formulation)	intramuscular	40–60 mg	every 4 weeks

Ranges are reported from the literature for research context only. They are not a protocol and not a recommendation.

Concentration by vial and diluent

Vial	1 mL diluent	2 mL diluent	3 mL diluent
2 mg	2,000 mcg/mL	1,000 mcg/mL	667 mcg/mL
5 mg	5,000 mcg/mL	2,500 mcg/mL	1,667 mcg/mL
10 mg	10,000 mcg/mL	5,000 mcg/mL	3,333 mcg/mL

Concentration is vial mass divided by diluent volume. Reconstitution volume changes what you draw, never the dose itself.

What to draw for 300 mcg

Vial	Diluent	Draw volume	U-100 units	Doses per vial
2 mg	1 mL	0.15 mL	15 units	7
2 mg	2 mL	0.3 mL	30 units	7
2 mg	3 mL	0.45 mL	45 units	7
5 mg	1 mL	0.06 mL	6 units	17
5 mg	2 mL	0.12 mL	12 units	17
5 mg	3 mL	0.18 mL	18 units	17
10 mg	1 mL	0.03 mL	3 units	33
10 mg	2 mL	0.06 mL	6 units	33
10 mg	3 mL	0.09 mL	9 units	33

Calculated for the low end of the reported Cushing's disease range. Change the dose in the calculator above for any other amount.

Pasireotide at a glance

~12 hours (SC); ~23 days (LAR)

Half-life

1,047.23 Da

Molecular weight

subcutaneous, intramuscular

Routes

prescription

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