Convert your Leuprolide dose
Vial
Result
Converted amount7,500 mcg
Dose mass7,500 mcg
Concentration2,500 mcg/mL
Draw volume3 mL
U-100 syringe300 units
Reported study ranges
| Purpose | Route | Reported range | Frequency |
|---|---|---|---|
| Advanced prostate cancer — ADT | intramuscular | 7.5–22.5 mg | every 1–3 months (depot) |
| Endometriosis or uterine fibroids | intramuscular | 3.75–11.25 mg | monthly or every 3 months (depot) |
| Daily subcutaneous injection (non-depot) | subcutaneous | 1–1 mg | once daily |
Ranges are reported from the literature for research context only. They are not a protocol and not a recommendation.
Concentration by vial and diluent
| Vial | 1 mL diluent | 2 mL diluent | 3 mL diluent |
|---|---|---|---|
| 2 mg | 2,000 mcg/mL | 1,000 mcg/mL | 667 mcg/mL |
| 5 mg | 5,000 mcg/mL | 2,500 mcg/mL | 1,667 mcg/mL |
| 10 mg | 10,000 mcg/mL | 5,000 mcg/mL | 3,333 mcg/mL |
Concentration is vial mass divided by diluent volume. Reconstitution volume changes what you draw, never the dose itself.
What to draw for 7,500 mcg
| Vial | Diluent | Draw volume | U-100 units | Doses per vial |
|---|---|---|---|---|
| 2 mg | 1 mL | 3.75 mL | 375 units | 0 |
| 2 mg | 2 mL | 7.5 mL | 750 units | 0 |
| 2 mg | 3 mL | 11.25 mL | 1,125 units | 0 |
| 5 mg | 1 mL | 1.5 mL | 150 units | 1 |
| 5 mg | 2 mL | 3 mL | 300 units | 1 |
| 5 mg | 3 mL | 4.5 mL | 450 units | 1 |
| 10 mg | 1 mL | 0.75 mL | 75 units | 1 |
| 10 mg | 2 mL | 1.5 mL | 150 units | 1 |
| 10 mg | 3 mL | 2.25 mL | 225 units | 1 |
Calculated for the low end of the reported Advanced prostate cancer — ADT range. Change the dose in the calculator above for any other amount.
Leuprolide at a glance
~3 hours (IV bolus); sustained release over weeks with depot formulations
Half-life
1,209.4 Da
Molecular weight
subcutaneous, intramuscular
Routes
prescription
Legal status