Convert your Histrelin dose
Vial
Result
Converted amount50,000 mcg
Dose mass50,000 mcg
Concentration2,500 mcg/mL
Draw volume20 mL
U-100 syringe2,000 units
Reported study ranges
| Purpose | Route | Reported range | Frequency |
|---|---|---|---|
| Central precocious puberty (children) | subcutaneous | 50–50 mg | one implant every 12 months |
| Advanced prostate cancer — ADT | subcutaneous | 50–50 mg | one implant every 12 months |
Ranges are reported from the literature for research context only. They are not a protocol and not a recommendation.
Concentration by vial and diluent
| Vial | 1 mL diluent | 2 mL diluent | 3 mL diluent |
|---|---|---|---|
| 2 mg | 2,000 mcg/mL | 1,000 mcg/mL | 667 mcg/mL |
| 5 mg | 5,000 mcg/mL | 2,500 mcg/mL | 1,667 mcg/mL |
| 10 mg | 10,000 mcg/mL | 5,000 mcg/mL | 3,333 mcg/mL |
Concentration is vial mass divided by diluent volume. Reconstitution volume changes what you draw, never the dose itself.
What to draw for 50,000 mcg
| Vial | Diluent | Draw volume | U-100 units | Doses per vial |
|---|---|---|---|---|
| 2 mg | 1 mL | 25 mL | 2,500 units | 0 |
| 2 mg | 2 mL | 50 mL | 5,000 units | 0 |
| 2 mg | 3 mL | 75 mL | 7,500 units | 0 |
| 5 mg | 1 mL | 10 mL | 1,000 units | 0 |
| 5 mg | 2 mL | 20 mL | 2,000 units | 0 |
| 5 mg | 3 mL | 30 mL | 3,000 units | 0 |
| 10 mg | 1 mL | 5 mL | 500 units | 0 |
| 10 mg | 2 mL | 10 mL | 1,000 units | 0 |
| 10 mg | 3 mL | 15 mL | 1,500 units | 0 |
Calculated for the low end of the reported Central precocious puberty (children) range. Change the dose in the calculator above for any other amount.
Histrelin at a glance
~3.9 hours (IV bolus); sustained release from implant over 12 months
Half-life
1,323.52 Da
Molecular weight
subcutaneous
Routes
prescription
Legal status