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Aviptadil dose calculator

Reported study range for pulmonary delivery (investigational inhaled/nasal): 100300 mcg twice daily (nasal). Convert it below, including draw volume and syringe units.

Convert your Aviptadil dose
Vial
Result
Converted amount0.1 mg
Dose mass100 mcg
Concentration2,500 mcg/mL
Draw volume0.04 mL
U-100 syringe4 units
Reported study ranges
PurposeRouteReported rangeFrequency
pulmonary delivery (investigational inhaled/nasal)nasal100300 mcgtwice daily
COVID-19 ARDS / acute respiratory failure (investigational IV protocol)intravenous166498 ng/kg/hrcontinuous infusion over 3 days (escalating)

Ranges are reported from the literature for research context only. They are not a protocol and not a recommendation.

Concentration by vial and diluent
Vial1 mL diluent2 mL diluent3 mL diluent
2 mg2,000 mcg/mL1,000 mcg/mL667 mcg/mL
5 mg5,000 mcg/mL2,500 mcg/mL1,667 mcg/mL
10 mg10,000 mcg/mL5,000 mcg/mL3,333 mcg/mL

Concentration is vial mass divided by diluent volume. Reconstitution volume changes what you draw, never the dose itself.

What to draw for 100 mcg
VialDiluentDraw volumeU-100 unitsDoses per vial
2 mg1 mL0.05 mL5 units20
2 mg2 mL0.1 mL10 units20
2 mg3 mL0.15 mL15 units20
5 mg1 mL0.02 mL2 units50
5 mg2 mL0.04 mL4 units50
5 mg3 mL0.06 mL6 units50
10 mg1 mL0.01 mL1 units100
10 mg2 mL0.02 mL2 units100
10 mg3 mL0.03 mL3 units100

Calculated for the low end of the reported pulmonary delivery (investigational inhaled/nasal) range. Change the dose in the calculator above for any other amount.

Aviptadil at a glance
~1–2 minutes (IV; rapidly cleared); designed for continuous infusion
Half-life
3,326.8 Da
Molecular weight
intravenous, nasal
Routes
prescription
Legal status
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